Scientific Programme

11th International Cell and Gene Therapy Conference (CGTCON 2026)

Friday, 09 & Saturday, 10 October 2026
Venue: New Examination Building, Christian Medical College Vellore, Bagayam Campus, Vellore 632002, Tamil Nadu, India
Organised by: Centre for Stem Cell Research (a Unit of BRIC-inStem, Bengaluru), Christian Medical College Vellore, Bagayam Campus, Vellore 632002, Tamil Nadu, India.
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Day 1 — Friday, October 9, 2026

Day 01 of 02
07:00 to 08:00 AM
REGISTRATION & BREAKFAST
08:00 to 08:15 AM
WELCOME ADDRESS HALL A
Parallel Sessions
Hall A
SESSION 1A: HEMATOLOGICAL DISORDERS 1
Chairs: Aby Abraham & Poonkuzhali Balasubramanian
08:30 to 08:55 AM Trends and outcomes of stem cell transplantation Biju George Christian Medical College Vellore, Vellore, India
08:55 to 09:20 AM Navigating the equitability barrier of gene editing therapies in India Debojyoti Chakraborty CSIR-Institute of Genomics & Integrative Biology (IGIB), New Delhi, India
09:20 to 09:45 AM Development of curative therapies for inherited anemias Senthil Bhoopalan St. Jude Children’s Research Hospital, Memphis, TN, USA
09:45 to 10:10 AM Recent Advances in CAR T-Cell Therapy for Hematologic Malignancies Vikram Mathews Christian Medical College Vellore, Vellore, India
Hall B
SESSION 1B: OCULAR DISORDERS
Chairs: Sanita Mary George Korah & Anupriya Arthur
08:30 to 08:55 AM Understanding Inherited Eye Diseases (IEDs) and Developing Newer Therapeutics Indumathi Mariappan BRIC-Institute for Stem Cell Science and Regenerative Medicine (inStem), Bengaluru, India
08:55 to 09:20 AM Future Directions in Corneal Regeneration: Convergence of Stem Cell Biology and Biomaterials Vivek Singh L V Prasad Eye Institute, Hyderabad, India.
09:20 to 09:45 AM Gene Therapy in Retinal Dystrophies: Real-World Effectiveness and Challenges Deepika Parameswarappa Narayana Nethralaya, Bengaluru, India
09:45 to 10:10 AM A synthetic splice-enhancer intron platform for efficient hybrid dual-AAV gene therapy: application in Stargardt disease Arkasubhra Ghosh Narayana Nethralaya Foundation, Bengaluru, India
10:10 to 10:30 AM
☕ TEA BREAK
Parallel Sessions
Hall A
SESSION 2A: CELL THERAPY FOR DIABETES
Chairs: Felix Jebasingh & Supraja Srivatsava
10:35 to 11:00 AM Beyond Insulin: Regenerating Beta Cells via Stem Cell Therapy versus Growth Factors Rohit Kulkarni Harvard Medical School, Boston, MA, USA
11:00 to 11:25 AM Genetic Forms of Lipodystrophy and Emerging Gene Therapy Strategies Aaron Chapla Christian Medical College Vellore, Vellore, India
11:25 to 11:50 AM Total Pancreatectomy with Islet Autotransplantation for Chronic Pancreatitis: An International Experience Gopalakrishnan Loganathan Otsuka American Pharmaceuticals, Minnesota, USA
11:50 to 12:15 PM Understanding targets at single-islet-cells for anti-diabetic treatment Nikhil Gandasi Indian Institute of Science (IISc), Bengaluru, India
Hall B
SESSION 2B: VIRAL & NON-VIRAL NUCLEIC ACID DELIVERY TECHNOLOGIES
Chairs: Suresh Rayala & Immanuel Dhanasingh
10:35 to 11:00 AM Metadherin-mRNA-LNPs for Triple-Negative Breast Cancer Therapy Srinivasa Reddy Bonam CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad, India
11:00 to 11:25 AM Engineering Controlled Destabilization: The “Magic Methyl” Effect in RNAi Enhancement Kiran R. Gore Indian Institute of Technology (IIT) Kharagpur, Kharagpur, India
11:25 to 11:50 AM Biomaterial-based acellular cancer immunotherapy Prakriti Tayalia Indian Institute of Technology (IIT) Bombay, Mumbai, India
11:50 to 12:15 PM Extracellular vesicles in cancer therapy Suresh Mathivanan La Trobe Institute for Molecular Science, Victoria, Australia
12:15 to 01:15 PM
🍽️ LUNCH & INDUSTRY EXHIBITION
Parallel Sessions
Hall A
SESSION 3A: CARDIOVASCULAR DISORDERS
Chairs: Sirish Chandra Srinath & Gayathri Bhuvaneswaran Kartha
01:30 to 01:55 PM Leveraging Human iPSC’s to Advance Hypertrophic Cardiomyopathy Treatment John Carter Ralphe University of Wisconsin, Madison, WI, USA
01:55 to 02:20 PM Organization principles governing the assembly and function of contractile units across scales Minhaj Sirajuddin BRIC-Institute for Stem Cell Science and Regenerative Medicine (inStem), Bengaluru, India
02:20 to 02:45 PM PRKCA variants cause hypertrophic cardiomyopathy in multi-ancestry patients, stem cell-derived cardiomyocytes, and pre-clinical models through ERK1/2 Dhandapani Perundurai BRIC-Institute for Stem Cell Science and Regenerative Medicine (inStem), Bengaluru, India
02:45 to 03:10 PM From Prenatal Biomarker to Therapeutic Target: Circular RNA-X in Hypoplastic Left Heart Syndrome Anupam Mittal Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
Hall B
SESSION 3B: METABOLIC DISORDERS
Chairs: Asha H.S. & Praveen Paul
01:30 to 01:55 PM Molecular and Functional characterization of patients with Mucopolysaccharidosis Ashwin Dalal BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India
01:55 to 02:20 PM Delving for precision care in Gaucher disease Sumita Danda Christian Medical College Vellore, Vellore, India
02:20 to 02:45 PM Molecular timing and scaling of hepatic gluconeogenic output during fed-fast transitions Ullas Kolthur Seetharaman BRIC-Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India
02:45 to 03:10 PM Gene therapy for liver inherited metabolic diseases Julien Baruteau University College London (UCL), Great Ormond Street Institute of Child Health, London, UK
Parallel Sessions
Hall A
SESSION 4A: NEUROLOGICAL DISORDERS
Chairs: Maya Thomas & George Mani
03:10 to 03:35 PM Beyond Conventional Antiseizure Medications: Small Molecules and Gene Therapies in Childhood Epilepsies Sangeetha Yoganathan Christian Medical College Vellore, Vellore, India
03:35 to 04:00 PM Next-generation gene therapy for neuromuscular disorders - Opportunities for global impact with indigenous solution. Jayandharan G. Rao Indian Institute of Technology (IIT) Kanpur, Kanpur, India
04:00 to 04:25 PM Gene therapy for Developmental Epileptic Encephalopathy - from Bench to Bedside Srinivasarao Repudi BRIC-Institute for Stem Cell Science and Regenerative Medicine (inStem), Bengaluru, India
04:25 to 04:50 PM Niemann–Pick Disease: From Molecular Diagnosis to Therapeutic Frontiers Neerja Gupta All India Institute of Medical Sciences (AIIMS), New Delhi, India
Hall B
SESSION 4B: TECHNOLOGY ADVANCES
Chairs: Aruna Rakha Arora & Jyothi Prasanna
03:10 to 03:35 PM Decoding Cell-State Transitions Through Enhancer  and Chromatin Dynamics Srinivas Animireddy BRIC-Institute for Stem Cell Science and Regenerative Medicine (inStem), Bengaluru, India
03:35 to 04:00 PM RBM3 mRNA delivery with functionalized lipid nanoparticles for improving muscle function Marepally Srujan Kumar Centre for Stem Cell Research, Christian Medical College Vellore, Vellore, India
04:00 to 04:25 PM Stem Cell Transplantation in Ischemic Heart: A Cure in Waiting - or a Battle for Survival Sanjay Kumar All India Institute of Medical Sciences (AIIMS), Bathinda, India
04:25 to 04:50 PM Translational potential of Human Liver organoids for chronic liver diseases: Deliberations From bench to bedside approaches Ruchi Tandon Translational Health Science and Technology Institute, Faridabad, Haryana, India
04:50 to 05:50 PM
☕ POSTER PRESENTATIONS/TEA
KEYNOTE ADDRESS - SCUDDER AUDITORIUM
Chairs: Sangeetha Yoganathan & Senthil Bhoopalan
06:00 to 06:45 PM
Gene Therapy for Leukodystrophies Christine Noel Duncan Harvard Medical School, Boston, MA, USA
06:45 to 07:30 PM
INAUGURATION AT SCUDDER AUDITORIUM Chief Guest: P Balaram Padma Bhushan, Distinguished Scientist, Former Director of Indian Institute of Science (IISc), Bangalore
07:30 PM Onwards
DINNER & CULTURAL PROGRAMME AT EDEN GARDEN

Day 2 — Saturday, October 10, 2026

Day 02 of 02
07:00 to 08:15 AM
REGISTRATION & BREAKFAST
Parallel Sessions
Hall A
SESSION 5A: HEMATOLOGICAL DISORDERS 2
Chairs: Eunice Sindhuvi & Sharon Anbumalar Lionel Ninan
08:30 to 08:55 AM Gene therapy for Hemophilia A Aby Abraham Christian Medical College Vellore, Vellore, India
08:55 to 09:20 AM Targeted base editing enables safe and efficient knockout of ELANE for the treatment of ELANE-associated severe congenital neutropenia Mohankumar Murugesan Centre for Stem Cell Research, Christian Medical College Vellore, Vellore, India
09:20 to 09:45 AM Precision conditioning for precision medicine: Targeted, Non-Genotoxic hematopoietic stem cell Conditioning to Enable Gene Therapy with Gene-Edited Stem Cells Saravanabhavan Thangavel Centre for Stem Cell Research, Christian Medical College Vellore, Vellore, India
09:45 to 10:10 AM A pharmacological modulator of Glucocerebrosidase reverses pathogenic phenotypes in Gaucher’s disease and GBA1-Parkinson’s disease Models Sivaprakash K Ramalingam Indian Institute of Technology (IIT) Kanpur, Kanpur, India
Hall B
SESSION 5B: ORGANOIDS & DISEASE MODELLING
Chairs: Sitara Swarna Rao & Ruchi Tandon
08:30 to 08:55 AM Human Intestinal Organoids as Models of Enteric Infections and Vaccines Sasirekha Ramani Baylor College of Medicine, Houston, TX, USA
08:55 to 09:20 AM Chromatinopathies, Ciliopathies, and Brain Malformations: From Genetic Mechanisms to Disease Models Bhavana Muralidharan BRIC-Institute for Stem Cell Science and Regenerative Medicine (inStem), Bengaluru, India
09:20 to 09:45 AM Disease modelling using iPSC Shaji RV Centre for Stem Cell Research, Christian Medical College Vellore, Vellore, India
09:45 to 10:10 AM Organs in a Dish: Intestinal and Liver Organoids for Human Disease Modelling Vijayalakshmi B Centre for Stem Cell Research, Christian Medical College Vellore, Vellore, India
10:10 to 10:30 AM
☕ TEA BREAK
Parallel Sessions
Hall A
SESSION 6A: MANUFACTURING AND REGULATORY ASPECTS IN CELL & GENE THERAPY
Chairs: Arkasubhra Ghosh & Gaurav Narula
10:35 to 11:00 AM In vitro prediction of CAR-T Cell Function, Persistence, and Therapeutic Success Priyadarshini Chatterjee MicroCRISPR Pvt. Ltd, New Delhi, India
11:00 to 11:25 AM Towards Accessible, Equitable, and Affordable Cell Therapy: The Promise of Allogeneic γδ CAR-T Cells Lakshmikanth S Gandikota Immuneel Therapeutics Private Limited, Bengaluru, India
11:25 to 11:50 AM Regulatory Aspects of Cell and Gene Therapy: Navigating the Indian Regulatory Pathway Akhil Kumar Journey to West, Singapore
11:50 to 12:15 PM Allogeneic Off-the-Shelf Natural Killer (NK) Cells for Autoimmune Disorders and Cancers Renjitha Gopurappilly NKure Therapeutics Pvt Ltd, (CCAMP), Bengaluru, India
Hall B
SESSION 6B: STEM CELL & GENE THERAPY - INDUSTRY UPDATES
Chairs: Sharat Damodar & Ruchika Goel
10:35 to 11:00 AM Navigating Our Way to Developing Next Generation CAR T Cell Therapy – The XenCART Model Gaurav Kharya Cellogen Therapeutics Pvt. Ltd., Noida, India
11:00 to 11:25 AM The Evolving Landscape of Mesenchymal Stromal Cell Therapy and Regulatory Considerations Pawan Kumar Gupta Stempeutics, Research Private Ltd., Bengaluru, India
11:25 to 11:50 AM Real world evidence (RWE) of efficacy and safety of Talicel Rahul Purwar Immunoadoptive Cell Therapy Private Limited (ImmunoACT) & IIT Bombay, Mumbai, India
11:50 to 12:15 PM A Phase 1/2a Clinical Trial of Allogeneic Retinal Pigmented Epithelium (RPE) cells in Geographic Atrophy (GA): Interim Results of Safety & Efficacy Jogin Desai Eyestem Research Private Ltd., (CCAMP), Bengaluru, India
12:15 to 01:15 PM
🍽️ LUNCH & INDUSTRY EXHIBITION
Parallel Sessions
Hall A
SESSION 7A: CAR T & CAR NK CELL THERAPY
Chairs: Mammen Chandy & Gaurav Kharya
01:30 to 01:55 PM The Cell-Gene Therapy Road Beyond B-Cell Malignancies Needs Smarter Strategies and not just Better CARs Gaurav Narula Tata Memorial Centre, Mumbai, India
01:55 to 02:20 PM Post CART cell therapy - complications Sharat Damodar Mazumdar Shaw Medical Center, Bengaluru, India
02:20 to 02:45 PM From Donor to Dose: Translating Allogeneic CAR-NK Cell Therapy Towards Clinical Reality Dinesh Kundu East Ocyon Bio, Gurugram, India
02:45 to 03:10 PM Generation and Preclinical Evaluation of TRAC/B2M Cytosine Base-Edited Allogeneic CD19 CAR-T Cells for B-ALL Thiyagaraj Mayuranathan Centre for Stem Cell Research, Christian Medical College Vellore, Vellore, India
Hall B
SESSION 7B: DERMATOLOGICAL DISORDERS
Chairs: Dharshini Sathishkumar & Diya Binoy Joseph
01:30 to 01:55 PM MicroRNA in Epidermolysis Bullosa—Pathophysiologic and translational Significance Vinod Kumar Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
01:55 to 02:20 PM Cell-based therapies from genetic to inflammatory skin disease Su Lwin King's College London (KCL), London, UK
02:20 to 02:45 PM Engineering Human Skin: Applications of 3D Skin Models in Dermatology Research Archana Singh CSIR-Institute of Genomics & Integrative Biology (IGIB), New Delhi, India
02:45 to 03:10 PM Accessible Diagnostics & Affordable Therapies for Incurable Genetic Skin Diseases Vamsi K. Yenamandra Sri Madhusudhan Sai Institute of Medical Sciences & Research (SMSIMSR), Chikkaballapur, India
Parallel Sessions
Hall A
SESSION 8A: INDUSTRY TALKS
Chairs: Barun Mahata & Alan Punnoose
03:10 to 03:30 PM Addressing ATMP manufacturing Risks through Closed Vial Technologies Shrikant Rao Pharmalab India Pvt. Ltd. (Representing Aseptic Technologies, Belgium)
03:30 to 03:50 PM Empowering Cell and Gene Therapy: Overcoming Bottlenecks with Innovative Agilent Cell Analysis Solutions Saket Siddharth Agilent Technologies, Hyderabad, India
03:50 to 04:10 PM Transforming Translational Research with Cell & Gene Therapy and Spatial Biology Solutions Asim Iqbal Shaikh Miltenyi Biotec, India.
04:10 to 04:30 PM From Process Development to GMP Execution - India's First Versatile Plasmid DNA Manufacturing Platform Bhushan Kantode & Kavya Kannan Kodo Lifescience Pvt. Ltd, Vapi, India
04:30 to 04:50 PM A Scalable Framework for CRISPR Off-Target Assessment Using Orthogonal Nomination and Targeted Deep Sequencing Edward Wong Serng Yuen Integrated DNA Technologies (IDT), Singapore
04:50 to 05:10 PM The Cell Therapy Reset: Redefining the Path Forward Through Modular Manufacturing and In Vivo Immune Engineering Vaibhav Daund Cytiva Ltd., India
Hall B
SESSION 8B: STUDENT PRESENTATIONS
Chairs: Joe Varghese & Sathish Kumar L
03:10 to 03:22 PM Generation of Human Corneal Epithelial Cells from induced Pluripotent Stem Cells in Serum-Free and Feeder-Free Conditions using a Chemically Defined Medium Vikram Krishna L V Prasad Eye Institute, India, India
03:22 to 03:34 PM Targeting IFITM2/3 to Enhance Lentiviral Transduction Efficiency in CD34+ Hematopoietic Stem and Progenitor Cells Shreejha Chandrasekar Shankara Cancer Hospital and Research Institute, India
03:34 to 03:46 PM Characterization and In Vitro Evaluation of the Regenerative Potential of Pooled Human Bone Marrow-Derived Mesenchymal Stromal Cell-Conditioned Medium for Diabetic Foot Ulcers Neema V Shetty Manipal Academy of Higher Education (MAHE), India
03:46 to 03:58 PM Developing Novel Immunotherapy Strategies for Treating Relapsed, CD20/CD19-Negative Diffuse Large B-Cell Lymphoma (DLBCL) Nandini Sharma Advanced Center for Treatment, Research, and Education in Cancer (ACTREC), India
03:58 to 04:10 PM Characterization of Paracrine and Neuroprotective Response of RPE Cells Under Oxidative and Cellular Stress Recapitulating AMD-Like Disease Conditions Nikshitha Ramanath Manipal Academy of Higher Education (MAHE), India
04:10 to 04:22 PM Cell-Penetrating Peptide-Based Gene Delivery for Potential Therapy of Autosomal Recessive Congenital Ichthyosis. Idrees Qadir Gojree CSIR Institute of Genomics and Integrative Biology, India
04:22 to 04:34 PM One-Time CRISPR Adenine Base Editing Intervention in SMA: From SMN2 Splice Correction to Motor Neuron Rescue Sheena P Kochumon Amrita Institute of Medical Sciences and Research Centre, India
04:34 to 04:46 PM Metabolically Optimized, CD19-Targeted Allogeneic CAR-T Cells Overcome Antigen Escape and Show Persistent Killing in B-Cell Malignancies Riya Agarwal MicroCrispr Pvt. Ltd., India
04:46 to 04:58 PM In Vitro Proof-of-Concept Evaluation of GD2-Specific CAR-Engineered Allogeneic γδ T Cells Against Solid Tumors Hascitha J Immuneel therapeutics Pvt. Ltd., India
04:58 to 05:10 PM Investigating ABI1 as a new cardiomyopathy gene using multi-ancestry patient-exomes, base-edited iPSCs and Knock-in mice models Saptashwa Chakrabarti BRIC-Institute for Stem Cell Science and Regenerative Medicine (inStem), India.
05:10 to 05:50 PM
POSTER PRESENTATION/TEA
KEYNOTE ADDRESS - SCUDDER AUDITORIUM
Chairs: Mammen Chandy & John Carter Ralphe
06:00 to 06:45 PM
From Innovation to Translation to Patients: The Future of Genetically Engineered T Cell Therapies Bruce Levine University of Pennsylvania, Philadelphia, PA, USA
06:45 to 07:30 PM
VALEDICTION, PRIZE DISTRIBUTION AND CONCLUSION AT SCUDDER AUDITORIUM
07:30 PM Onwards
DINNER AT CENTRE FOR STEM CELL RESEARCH